Two cases of leukemia which were treated periodontically under diagnosis of marginal periodontitis and hyperplastic gingivitis respectively are presented.
Case 1, a 44-year-old female received periodntal treatments such as dosage and irrigation at two dentists and one oto-rhinolaryngologist complaining of gingival swelling and general fatigue. Because of no response to such treatment, the patient was referred to our hospital for investigation. Clinical examination showed a pale woman with gangrenous stomatitis, submandibular lymphadenopathy and extreme fatigue. Haematological test confirmed the diagnosis of acute myelogenous leukemia. Despite of oral and systemic treatment, the patient was dead 2 weeks after admission, 2 months after the first dental visit.
Case 2, a 35-year-old female, compaining of gingival swelling, cervical lymphadenopathy and easy fatigue, received dental treatments such as scaling, irrigation, tooth extraction, alveolar osteoplasty and caries restoration at two dentists, and medication at one surgeon. However, there was no improvement of gingival swelling, and the patient was referred to our hospital for precise examination. On admission, the patient was pale and easily fatigued. Gingival swelling and general lymphadenopathy were presented, and peripheral blood examination revealed acute myelogenous leukemia. Despite of treatments with blood transfusion and chemotherapy, the patient was dead about 1 year after the first dental visit.
