Photo-crosslinked Porous PEG Hydrogel Membrane via Electrospinning

Abstract

We report the fabrication and the characterization of photo-crosslinked porous hydrogel membrane via the electrospinning. Poly (ethylene glycol) (PEG) nanofibers were extruded and deposited on poly(ethylene glycol) diacrylate (PEG-DA) macromer, and then they were photo-crosslinked. The morphologies of these photo-crosslinked membrane, especially dimension of porous holes were investigated and it was found that they could be controlled from particle-like shapes to fibrous shapes by PEG concentration. These hydrogel membranes showed high degree of porous morphologies with holes of diameters from 0.78 to 2.4 μm. Therefore, it presents good opportunities for biosensors or biofilters due to surface to volume ratio.