抄録
A droplet-born air-blowing method is the advanced method of the drawing lithography enables simple and fast fabrication, which doesn't require UV irradiation or laser. However, it has disadvantages such as low throughput in the formation of droplet array as it uses the dispenser to make droplets one by one. In order to increase the throughput with simplifying the fabrication method, we suggest a novel fabrication method for microneedles array (MNs array) using the shadow mask, which can fabricate microneedles array uniformly. In addition, our method enables to control the amount of polymer in microneedle by adjusting the hole dimension as well as the thickness of a shadow mask. We here established the use of a shadow mask to form multiple droplet array at one time and then achieved microneedles array from the droplet array by drawing lithography within a few minutes. We anticipate that shadow mask assisted drawing lithography will be suitable to improve the fabrication throughput of dissoluble microneedle for new generation of drug delivery system.
