An aseismic reinforcement of existing medical facilities such as an important hospital that building function and emergency medical services would be needed in a large earthquake is themes in this paper. First, the damage situation of hospitals in the Great East Japan Earthquake, the typical damage events of buildings and a characteristic of damage examples in medical facilities were shown as a characteristic of material damages by earthquakes. Then, the progress situation of the aseismic reinforcement for existing medical facilities were shown, and necessity of further promotion of the reinforcement for the building structure and importance of grasping the progress of the earthquake proofing for nonstructural components and medical equipment in detail were emphasized. Next, some essential points for the seismic retrofitting of the building structure, nonstructural components and medical equipment were highlighted to perform effective aseismic reinforcement for existing medical facilities. Finally, the seismic isolation retrofit, as the most effective method for seismically upgrading of existing medical facilities that need to ensure not only the safety of buildings but also the operability of medical treatment, was introduced.