A Study of Multiple View Lung Scintigraphy with ^99mTc-MAA

Abstract

Fundamental and clinical investigation were carried out with^99mTc-MAA which was prepared in our laboratory using“Techne-MAA-Kit”. Radiochemical purity of^99mTC-MAA by paper chromatography was about 98% and stable after tagging during 3 hours of observation. In addition, radioactivity over the lung after injection was very high by linear scan.
One hundred and seven cases were subjected to study. All scintiphotos were taken by means of anterior, posterior, left and right laterals projection using gamma camera. Especially, in 43 cases of lung cancer, detectability of perfusion deficits in each projection was investigated in comparison with the roentgenograms. As a result, it was found that perfusion deficits in located segmental lesion were frequently undetected by the anterior or posterior scintiphotos but were well defined in the lateral views. Multiple view are therefore necessary in the case of routine examination and the application of^99mTc-MAA is very appropriate in order to save a time for us.