抄録
To investigate the activity of cholinesterase in erythrocytes and to make its measurement a routine examination, it was conducted to measure by automation using propionyl thiocholine.
As the result, it was found that the method has good correlation with acetyl thiocholine method and phenol red method, and also has good sensitivity in both erythrocytes and serum, therefore microanalysis is thought to be possible.
In the measurement of cholinesterase, it was revealed that the erythrocyte cholinesterase in leukemia and myeloma is decreased, while that in polycythemia vera and iron deficiency anemia shows high value. In various cancers the activity of erythrocyte cholinesterase was almost normal. Because of the good correlation between cholinesterase and severity in leukemia its measurement seems to be useful in diagnosis and treatment of leukemia.
