抄録
Observations were made on erythropoiesis before, during and after blood transfusion in three cases with erythroleukemia. A marked decrease was seen in marrow erythroblasts, peripheral reticulocytes and plasma iron turnover in association with the rise in hemoglobin level. Plasma erythropoietin concentration, which had shown a conspicuous elevation in two of the three cases before initiation of transfusion, was reduced to hardly, if any, detectable level after the transfusion therapy.
These results indicate that erythropoiesis in erythroleukemia is regulated by erythropoietin elaborated in response to hypoxia as in physiological conditions.
