抄録
A 7-year-old boy was seen at Ohashi Branch Hospital of Toho Univ. on Jan. 21, 1971, with a chief complaint of anemia and abdominal distension. A diagnosis of chronic myelogenous leukemia was made from the peripheral and bone marrow smears, a low score of leukocyte alkaline phosphatase and a positive philadelphia chromosome (Ph').
On July 1973, the initial sign for blast crisis……fever, anemia, joint pains and gradual enlargement of liver and spleeen in association with high rate of blasts in peripheral blood ……was observed, and Ph' with deficiency of the No. 7 chromosome was recognized.
On Oct. 1973, the tumors were observed on the arm, head, chest and the lower part of the leg and grew larger in size. Biopsy of the cubital tumor revealed the leukemic infiltration with immature cells of myeloid series (myeloblastoma).
