抄録
DIC was induced by infusion of provocative dose of endotoxin and tissue extract of gastric cancer into normal rabbits pretreated of the blockage of RES. But it was not induced after infusion of these substances into thrombocytopenic rabbits pretreated with Busulfan and with blockage of RES. DIC was not also induced after antiplatelet serum into normal rabbits without previous blockage of RES, but in these cases prominent drops of platelet counts and release of PF4 into plasma were observed. In the present study the attempt has been made to investigate the interrelation between the required level of platelet count, the requirements of trigger substances and the blockage of RES in the DIC.
