抄録
A case of plasma cell dyscrasia, which was difficult to diagnosis, with polyneuropathy and endocrine disorders has been reported: on admission, a 47-year-old male had various clinical signs, such as pigmentation, hard hairs, edema and paresthesia on his extremities, gynecomastia, choked disk, and pseudopolycythemia, suggesting polyneuropathy and endocrine disorders. He has also chronic constrictive pericarditis and gastric ulcer. Acetate cellulose membrane electrophoresis revealed IgG (λ) M protein in both serum and spinal fluid. However, no Bence-Jones protein in urine nor plasmacytosis in bone marrow smears was detected. At that time a diagnosis was not made. After years plasmacytoma was demonstrated by the biopsy of right ishium. Therefore, Melphalan was given that was effective for his clinical symptoms and his M protein disappeared further.
