抄録
The patient was a 11 1/12-year-old girl who was admitted to our hospital because of anemia and bleeding tendency. On admission, promyelocytes were present as many as 16% of leukocytes in peripheral blood and 90% of nucleated cells in bone marrow. She developed fibrinogenopenic bleeding and laboratory evidences for disseminated intravascular coagulation.
The electron micoscopy revealed peculiar configurations of rough-surfaced endoplasmic reticulum (rough ER) and honeycomb-like inclusions in the organelle. The peculiar configurations of rough ER consisted of central locus with regular arrangement of round cisternae and multiple cisternae of rough ER radiating from the locus. The honeycomblike inclusions in rough ER were observed in about 16% of the leukemic cells.
