抄録
A 66-year-old woman was admitted at the Tokyo University Hospital, because of anemia and abnormal chest shadow. The anemia was normochromic and normocytic. There were no leukopenia or thrombocytopenia. Reticulocyte count was 0‰. Bone marrow aspiration revealed marked erythroid hypoplasia (0.2%), but there were no abnormalities on myeloid series and megakaryocytes. The diagnosis of PRCA was made. A biopsy of the mass in the chest showed thymoma (mixed type).
Prednisolone 60mg per day was administered. After twenty days, the size of the thymoma decreased remarkably, and then marked reticulocytosis was observed. No relapse of PRCA had been observed until her death.
Three hundred and seventy-four days after admission, she died of such complications as infection and cerebro-vascular thrombosis. An autopsy was made. Erythropoiesis was observed in the bone marrow, and a scared mass was found in the place of the thymoma. The histological study revealed very rarely scattered infiltrations of thymoma cells.