慢性鉛中毒による貧血

抄録

We report a case of anemia due to chronic lead poisoning. A 46-year-old female was admitted to our hospital because of general fatigue and anemia. A peripheral blood smear showed basophilic stippling. There was basophilic stippling and nuclear dysplasia of erythroblasts in the bone marrow. Laboratory findings were as follows: RBC 296×10⁴/μl, Hb 8.5 g/dl, blood lead concentration 67 μg/dl, urinary lead concentration 309 μg/l, blood δ-ALA dehydrase 0.03 μmol/ml, urinary δ-ALA 25.2 mg/l, urinary coproporphyrin 8,810 μg/g·Cr, and blood protoporphyrin 612 μg/dl. Chronic lead poisoning was diagnosed and she was treated with Ca-EDTA.