臨床血液
Online ISSN : 1882-0824
Print ISSN : 0485-1439
ISSN-L : 0485-1439
短報
髄外造血所見を伴う皮膚浸潤を認めた骨髄異形成/骨髄増殖性腫瘍 分類不能型
吉田 全宏堀内 美令植田 英也萩原 潔通金島 広中尾 隆文平田 央井上 健山根 孝久
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ジャーナル 認証あり

2015 年 56 巻 7 号 p. 911-914

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Cutaneous extramedullary hematopoiesis has been reported in a small number of patients with myelofibrosis. A 79-year-old male with JAK2V617F-positive myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS-MPN-U), presented with multiple skin lesions. The skin lesions were papulonodular, reddish brown, and elastic hard on palpation. Based on a lesion biopsy, cutaneous extramedullary hematopoiesis associated with MDS/MPN-U was diagnosed. He died four months later due to exacerbation of MDS/MPN-U. Cutaneous invasion might be associated with progressive disease and a poor prognosis for MDS/MPN-U, as it is for myelofibrosis.
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© 2015 一般社団法人 日本血液学会
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