抄録
By means of the standard and heated fibrin plate method the fibrinolytic activity of bone marrow from patients with various blood diseases was studied. For the measurement of fibrinolytic activity the euglobulinic precipitates obtained from the venous blood and the bone marrow aspiration were used.
In normal and pathological conditions the level of plasmin activity of bone marrow was higher than of peripheral blood and specially in cares with acute leukemia, macroglobulinemia, multiple myeloma and essential thrombocytopenic purpura the plasmin activity was remarkable.
The level of plasminogen activator in bone marrow was also higher than in venous blood. Leukopoietic and thrombocytopoietic disorders as well as dysproteinemias showed markedly high activator activity. And it was imagined from these findings that plasminogen might be activated to plasmin in bone marrow.
