臨床研究
血液疾患における好中球アルカリホスファターゼ活性値およびその変動因子について
1968 年 9 巻 2 号 p. 313-317
詳細
1968 年 9 巻 2 号 p. 313-317
A) Neutrophil alkaline phosphatase activities (NAP) of 70 materials from 47 patients with various blood disorders were measured.
Eleven cases with pancytopenia had normal or elevated NAP scores, and there was no demonstrable difference of NAP score between typical and atypical aplastic anemias.
Of 4 cases with PNH, 2 cases with typical PNH showed low NAP scores, in the other 2 cases with aplastic PNH syndome NAP scores were elevated.
In 7 cases with acute leukemia, NAP scores were varied from low to high.
B) As there were two peaks in distribution of grade of NAP in CML and PNH, it is assumed that those diseases had two cell lines in neutrophils, while typical aplastic anemia one.
C) Number of neutrophils and number of lobes of nuclei in neutrophils have no correlation with NAP score.
