We observed 11 patients who stayed in the Yamada Red Cross Hospital from June 1949 to December 1949, and measured their plasma protein fractions by electrophoreses. At the sametime, we examined dextrose double examination (Hagedorn-Yensen), serum N-P-N, serum-Cl (Koranyi-Ruszniak), serum-Ca (Krammer-Tisdall), sedimentation rate of red blood cells (Westergren), plasma bilirubin (Meulengracht), serum-Co (Inoue) and serum-Cd (Fujita-Iwano).
Conclusion
1) In biliary liver cirrhosis total plasma protein and albumin decreased (43.5-43 per cent), and especially after every ascites puncture. Alpha-globulin decreased. The increase of beta-globulin was not always proportional to the quantity of plasma bilirubin. Gamma-globulin increased (22.7 per cent). Both died after leaving the hospital.
2) In biliary liver cirrhosis and subacute hepatatrophia albumin decreased and the increase of beta-globulin was not alway proportional to the quantity of plasma bilirubin. In subacute hepatatrophia gamma-globulin increases (35.5 per cent).
3) Obstructive jaundice (2 cases)
The one died from insufficiency of liver function, the other completely cured. Albumin decreased (34.5-42.4 per cent).
4) Simple jaundice (3 cases)
All patients were completely cured. In all cases. serum protein did not decreased, but on the contrary, it increased in one of them. In all cases, albumin decreased at first, but after leaving the hospital, a normal conditions was regained. The increase of beta-globulin was almost proportional to the quantity of poasma bilirubin.
5) Dextrose double examination.
Fatal cases (3 cases; Staub (-), 2 cases; Staub (+)). Others; Staub (+).
6) Serum N-P-N.
In subacute hepatatrophia, the value increased (93.2mg/100cc), in all others, normal.
7) Serum Cl, normal.
8) Serum Ca, normal.
