抄録
Chemotaxis of the slime mold Physarum polycephalum for various cosmetic ingredients was investigated in relation to their effects on the skin using double-chamber method.
The effect of these agents on the slime mold appeared in the far lower concentration range than at general safety evaluation tests for animals such as guinea pigs and rabbits.
The slime mold exhibited negative chemotaxis for all the cosmetic ingredients tested.
The relationship was recognized between the threshold concentration of cosmetic ingredients for chemotaxis of slime mold and their toxicity (LD50 etc) in general test animals.