4 歯周ポケットにおける病原酵素産生菌の分布 (例会抄録(第428回))

抄録

I examined the production of the hydrolytic enzymes β-lactamase, DNase, hyaluronidase, chondroitin sulfatase, lipase, lecithinase, collagenase trypsin, chymotrypsin and viscous material in clinical strains isolated from periodontal pockets with and without acute inflammation.
In pocket bacteria with acute inflammation, the distribution of collagenase, DNase and trypsin producers was 30.4, 22.6 and 17.6%, respectively. Other hydrolytic enzyme-active bacteria were found in less than 5% of all isolates. P. gingivalis predominated as collagenase (33.9%), DNase (35.7%) and trypsin (82.9%) producers, respectively. The ratio of the above enzyme producers was lower in cases without acute inflammation than in active cases, but higher in cases without acute inflammation than in acute periapical periodontitis cases, indicating that pocket bacteria have considerable potential to induce acute inflammation.