2008 年 71 巻 2 号 p. 182-
I performed histological observations and measured the torque required to remove dental implants from rabbit femurs where Biopex-R^[○!R] had been placed in the gaps surrounding the implants. The removal torque was greater than 35 N・cm one week after the operation. Histological observation indicated there was no connective tissue interface between Biopex-R^[○!R] and the original bone. No inflammatory reactions were observed 8 weeks after the operation, and the biocompatibility of Biopex-R^[○!R] was very good. The results indicated that Biopex-R^[○!R] integrated directly to the original bone at an early stage. The strength of the removal torque should be adequated for initial fixation of the implant.