Skin Cancer
Online ISSN : 1884-3549
Print ISSN : 0915-3535
ISSN-L : 0915-3535
悪性血管内皮細胞腫の1例
林 大海森 弘樹梅田 整小原 宏之横山 明子飯田 秀夫西岡 清
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1996 年 11 巻 3 号 p. 461-464

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A 78-year-old man with malignant hemangioendothelioma on the scalp was successfully treated with a surgical operation and intra-arterial injection of recombinant interleukin-2 (rIL-2).
A tumor grew on his forehead after he stabbed with his comb 5 months ago. He visited our hospital with the skin lesion, measuring 6×3cm, after local excision of a mass at another clinic. Histologically, the tumor showed irregular vascular channels and bleeding, and the tumor cells showed positive factor VIII-related antigen.
Extensive resection and reconstruction using the lattisimus dorsi myocutaneous flap was performed in May, 1995. Intra-arterial injection of rIL-2 through a catheter at the right superficial temporal artery started just before the operation.
At his 14-month postoperative evaluation, he had no evidence of any recurrences and metastases.
It is suggested that extensive resection and intra-arterial injection of rIL-2 before and after the resection are effective to an early malignant hemangioendothelioma.
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