Eccrine porocarcinoma arising in Bowen's disease lesion with colon cancer
2001 年 16 巻 1 号 p. 37-40
詳細
2001 年 16 巻 1 号 p. 37-40
A 76-year-old man had a tumor on the right lower leg for a year. It was a diameter 3cm, reddish-brown. There was an ulcer of a diameter 2cm on the center of the tumor and a hyperkeratotic leision around the ulcer. Histopathologically, in the center of the speciman, there were islands of squamoid and basaloid tumor cells with necrosis of central areas, ductal luminas, and direct contination with normal epidermis. It was considered eccrine porocarcinoma. In the peripheral of thespeciman, there was an acanthotic leision with mitosis, keratinocytic atypia, and multinucleation. We considered it was Bowen's disease. Imunohistochemically, eccrine porocarcinoma expressed a cytokeratin pattern which was different from Bowen's disease. We considered our case was Bowen's disease with invasive carcinoma.
The patient had the examination for internal malignancy, and a colon cancer was discovered. [Skin Cancer (Japan) 2001; 16: 37-40]
