1992 年 2 巻 1 号 p. 55-62
To measure energy consumption during the process of chewing gum, and to investigate the effects of gum-chewing on levels of sugar and lipids in blood and pituitary - adrenal hormones concentrations in plasma, a study was designed in which nine healthy male volunteers chewed two pieces of marketed gum (6.18g;E-gum) for ten minutes with a chewing rhythm of about 80 times per minute while oxygen intake (VO2) and heart rate (HR) were measured continuously for 30 minutes before (rest period), during the 10 minutes (chewing period) and for 30 minutes after chewing (recovery period). Blood samples were drawn before, immediately after, 10 minutes and 30 minutes after gum-chewing via a catheter introduced into the brachial vein for measurements of blood sugar (BS), FFA, TG plasma ACTH, plasma adrenaline (pAd), noradrenaline (pNorad), and insulin (IRI) concentrations. Two pieces of the control gum (1.30 g; C-gum), a gum base containing no additional elements and harder than E-gum, were also chewed in the same manner as the E-gum. Both E- and C-experiments were carried out continuously in the sitting position and fasting state in no particular order, separately, during a different period between 10 a.m. and 2 p.m.