Journal of the Society of Powder Technology, Japan
Online ISSN : 1883-7239
Print ISSN : 0386-6157
ISSN-L : 0386-6157
Change of Molecular States of Drug by Ground with Cyclodextrin
Kouhei TsuchitoYasuo YoshihashiEtsuo YonemochiKatsuhide Terada
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2011 Volume 48 Issue 9 Pages 612-617

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Abstract
By co-grinding with β-cyclodextrin and drugs, it is suggested that drugs were included to β-cyclodextrin cavity. Ground mixture is amorphous, so that it is difficult to analyze the effect of co-grinding. This study was brought out molecular states of ground mixture and effect of co-grinding. It is suggested that change of molecular states by co-grinding was according to structure of drugs.
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© 2011 The Society of Powder Technology, Japan
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