1994 年 6 巻 3 号 p. 77-81
During the past 10 years, 18 patients with palatine tonsil cancer (all squamous cell carcinomas) were treated in the Department of Otorhinolaryngology of Mie University Hospital. Seven patients (39%) had stage II or III, and 11 (61%) had stage IV carcinoma. The cumulative 5-year survival rate was 50%. All patients were treated with irradiation therapy with or without simultaneous chemotherapy. Salvage operations were performed in 5 patients with residual cancer and radical neck dissection in 10 patients with a cervical mass. Six patients received intra-arterial chemotherapy simultaneously. The original tumors of the 6 patients were controlled by the combination of irradiation and simultaneous intra-arterial chemo-therapy. The 5-year cumulative survival rate was 82% for the patients treated with the combination therapy, and 36% for those who did not receive intra-arterial chemotherapy. We conclude that combination therapy is effective in the treatment of the original tumor of palatine tonsil cancer.