抄録
Effects of polynuclear aromatic hydrocarbons on the mutagenic activity of nitro aromatic compounds were investigated by the pre-incubation method using Salmonella typhimurium strain TA98 without S-9 mix.
Pyrene gave an enhancing effect for the mutagenicity of trinitrochlorobenzene. On the other hand, pyrene or BaP gave inhibitory effects for the mutagenicity of tetramitrocarbazole. Formation of charge-transfer complex was suggested for one of reason of these effects.
