The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Regular Contributions
A Protein in the Cell Wall of Helicobactor Pylori Binds Human IgG Deprived of Sugar Chains
Yutaka MasudaToshihiro Sugiyama
著者情報
ジャーナル フリー

2001 年 194 巻 1 号 p. 65-69

詳細
抄録
We found a protein binding non-antibody human IgG in Helicobactor pylori cell wall, when the IgG was enzymically deglycosylated. The protein had the amino acid sequence AEDGAHVAFM. IgG of H. pylori patients also bound to the protein and the IgG lost the sugar chain structure reactivities. These findings indicate that H. pylori binds human IgG without the sugar chains on its cell wall and suggest that H. pylori infection has a relation to the human IgG deglycosylation.
著者関連情報
© 2001 Tohoku University Medical Press
前の記事 次の記事
feedback
Top