抄録
The fine structure of eosinophiles, plasma cells and macrophages in the allergic nasal mucosa were studied by electron microscopy. The eosinophiles contained many granules with multiple crystals, eccentrically located nuclei, small Golgi apparatus, occasional GER and dispersed free ribosomes. The plasma cells showed structures comparable to the cells in the normal tissue, being filled with closely spaced GER and occasional mitochondria. Villous surface folds, which partly exhibited a reticular pattern, were quite frequently observed. The macrophages were considerably variable in shape, showing pseudopodia with many villous folds on the surface. Many pinocytotic and/or coated vesicles and occasional cup-like indentations were seen adjacent to the plasma membrane. Very close associations of eosinophiles with plasma cells and macrophages were commonly observed in the present specimens. It seems likely that these features represent a part of the defense reactions against foreign antigens in the connective tissue of the nasal mucosa.
