The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Pedigree Analysis of Growth Inhibition of Rat Hepatoma Cells, Culb TC, after Gamma Irradiation
MASATOSHI SAKKAHAJIM KATSUTATOSHIKO TAKAOKA
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1972 年 106 巻 3 号 p. 275-284

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抄録
Cultured rat hepatoma cells were irradiated with 500 to 800 R of gamma rays and inhibition of cell growth was recorded on cinemicrograms. Analysis of constructed pedigrees of control and treated cells indicated that (1) usual type of frequency distribution of generation time did not apply to control cells, (2) death after irradiation took place quite at random, (3) natural death in control occurred more frequently in pedigrees with less divisions, and (4) in some instances pedigrees with more divisions were more resistant to radiation-induced death.
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© Tohoku University Medical Press
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