1973 Volume 111 Issue 3 Pages 219-227
A 46-year-old housewife was admitted to the Tohoku University Hospital on July 2, 1972, because of fatigability, palpitation, weight loss and sweating. She had been administered orally 3.0 mCi of radioactive iodine for the treatment of hyperthyroidism in November, 1971. Both BMR (+30%) and thyroidal 24-hour uptake of 1311 (52%) were high. Resin sponge 131I-T3 uptake was 38%, serum total and free T4 were 11.8 μg/dl and 5.1 ng/dl, binding capacity of TBG and TBPA were 17.0 and 254 μg/dl, respectively. All these values were within normal range. 131I uptake of the thyroid was not suppressed by T3. Plasma TSH was not detectable by radioimmunoassay, but normal plasma TSH response was observed by the intravenous injection of 500 μg of TRH. Radioimmunoassay of T3 revealed elevated total and free T3, 365 ng/dl and 12, 800 pg/dl, respectively. Under the diagnosis of T3-thyrotoxicosis, daily dose of 10 drops of Lugol's solution was administered. After the treatment with Lugol's solution for four months, both BMR and serum total T3 became normal and her complaints disappeared, and no signs of hyper- and hypothyroid-ism were observed. The significance of iodide treatment is discussed in such cases.
