MnCl2 induced negative dromotropic effect on the AV node of dogs in situ. At a dose level above 10mg, a transient AV block was observed. The injection of 1-3mg of MnCl2 suppressed the acceleration of AV nodal rhythm, which was induced by administration of 1 μg of norepinephrine.
About this Journal The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920
by professors of Tohoku Imperial University, Medical School.
The TJEM has been published continuously, except for the year of 1946
just after the World War II.
The TJEM is open to original articles in all branches of medical
sciences.
The TJEM also covers the fields of disaster-prevention science,
including earthquake archeology.
Subscriptions Inland subscriptions should be sent to Tohoku University Medical
Press, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JAPAN.
Subscriptions from abroad should be addressed to MARUZEN CO., LTD.,
EXPORT DEPARTMENT,
Postal address: P.O.Box 75, Shinagawa, Tokyo 140-8799, JAPAN.
e-mail: export@maruzen.co.jp
