1976 Volume 118 Issue 1 Pages 45-51
Proteolytic pH-activity curve and agar gel electrophoretic pattern of acid proteolytic zymogens in serum and urine were studied in totally gastrectomized patients. In serum, total gastrectomy was found to reduce proteolytic activity markedly, but no appreciable changes could be detected by electrophoretic analysis. In urine, however, in addition to the marked reduction of proteolytic activity, changes were found in electrophoretic pattern after total gastrectomy. Namely, fraction Pg 3 tended to persist, while Pg5 disappeared along with the lapse of time after total gastrectomy. An unusual appearance of fraction Pg 7in urine was also observed on the occasion of postoperative transient albuminuria. Their origins and related clinical problems were discussed.
