The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
An IgG M-Component Reacting with Both Anti-κ and Anti-λ Light Chains in Multiple Myeloma
SEIJU ONODERA, RYUTARO INABA, ISAO SATO, KAZUYASU ENDO, TAKASHIRO SUZUKI, OSAMU KITAHARA, KATSUKO TAKAIIASHI, SHIGEO SUZUKI, YUKIO IMAMURA
Author information
Keywords: multiple myeloma, IgG-IM component, reaction with both Anti-κ and anti-λ
JOURNAL FREE ACCESS

1976 Volume 120 Issue 3 Pages 269-275

Details
Download PDF (2078K)
Download citation RIS

(compatible with EndNote, Reference Manager, ProCite, RefWorks)

BIB TEX

(compatible with BibDesk, LaTeX)

Text
How to download citation
Contact us
Abstract

A patient with multiple myeloma who has an IgG-IM-component in serum reacting with both κ and λ light chains in im-munoelectrophoresis is presented. The possibility of ‘hybrid molecule (H2LκL λ)’ is strongly suspected. The absorption studies of the patient's serum employing Anti-κ and anti-A light chains, however, support the view that this apparently single M-component consists of two M-components, IgG 1-κ and IgG 1- λ. The reason why these two M-components possessed the identical electrophoretic mobility is unclear. The possibility is high that these two M-components are produced in the same cell.

Content from these authors
© Tohoku University Medical Press
Previous article Next article
Favorites & Alerts

Recently viewed articles
  • About this Journal
    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.

  • Submitted manuscripts will be screened for plagiarism with Similarity Check (https://www.crossref.org/services/similarity-check/).
Announcements from publisher
  • Subscriptions
    Inland subscriptions should be sent to Tohoku University Medical Press, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JAPAN.

    Subscriptions from abroad should be addressed to MARUZEN CO., LTD., EXPORT DEPARTMENT, Postal address: P.O.Box 75, Shinagawa, Tokyo 140-8799, JAPAN. 
    e-mail: export@maruzen.co.jp
Share this page
feedback
 Top