The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Systemic Candidiasis Produced by Oral Candida Administration in Mice
TAKUSEI UMENAI
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1978 Volume 126 Issue 2 Pages 173-175

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Abstract
Systemic Candida infection from the gastrointestinal tract was examined in mice. Candida albicans was undetectable in the blood, lungs, spleen, liver or kidneys of mice 24hr after oral Candida administration even under condition of severe damage to the host defence system, but became detectable in the liver and kidneys of mice when they received combined treatment of antibiotics, x-ray irradiation and dexamethasone 3 and 5 days after oral Candida administration.
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© Tohoku University Medical Press
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