The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
A Role of Guanosine 3', 5'-Monophosphate in Human-Prolactin-Induced Estrogen Production by Feminizing Adrenal Neoplastic Cells
NOBUAKI FURUHASHI, VICTOR S. FANG
Author information
Keywords: hPRL, cGMP, estrogen, cAMP
JOURNAL FREE ACCESS

1980 Volume 132 Issue 1 Pages 87-92

Details
Download PDF (293K)
Download citation RIS

(compatible with EndNote, Reference Manager, ProCite, RefWorks)

BIB TEX

(compatible with BibDesk, LaTeX)

Text
How to download citation
Contact us
Abstract

Using feminizing adrenal neoplastic gland (FANG) cells we showed that hPRL stimulated cGMP biosynthesis. Also we could clearly demonstrate a stimulatory effect of db-cGMP plus theophylline on estrogen production without concomitant stimulation of cell growth. These findings indicate that a stimulatory effect of hPRL on estrogen biosynthesis by Fang-8 cells may act via increased cGMP concomitant with depressed CAMP.

Content from these authors
© Tohoku University Medical Press
Previous article Next article
Favorites & Alerts

Recently viewed articles
  • About this Journal
    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.

  • Submitted manuscripts will be screened for plagiarism with Similarity Check (https://www.crossref.org/services/similarity-check/).
Announcements from publisher
  • Subscriptions
    Inland subscriptions should be sent to Tohoku University Medical Press, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JAPAN.

    Subscriptions from abroad should be addressed to MARUZEN CO., LTD., EXPORT DEPARTMENT, Postal address: P.O.Box 75, Shinagawa, Tokyo 140-8799, JAPAN. 
    e-mail: export@maruzen.co.jp
Share this page
feedback
 Top