The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
'Nephritic Factor' May Be an Autoantibody to C3b or C4b
MASAHIRO ARAKAWAJIN SEINOTAKASHI FURUYAMA
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1981 Volume 133 Issue 4 Pages 481-482

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Abstract
ARAKAWA, M., SEINO, J. and FURUYAMA, T. 'Nephritic Factor' May Be an Autoantibody to C3b or C4b. Tohoku J. exp. Med., 1981, 133 (4), 481-482-We attempted to clarify the character of 'Nephritic Factor' in the alternative (NeFA) and classical pathways (NeFC) of the complement, using an agglutinating and a hemolytic activity assay. The results suggested a possibility that NeFA and NeFC were different in their ability but might appear at the same time in some cases, and that NeFA was anti-C3b autoantibody and NeFC anti-C4b autoantibody.
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