The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Effect of Isoproterenol on Regional Pulmonary Perfusion in the Reimplanted Lung of the Dog
TOYOHARU ISAWA, TAKEO TESHIMA, TOMIO HIRANO, AKIO EBINA, KOICHIRO SHIRAISHI, YOICHI FUKUDA, KIYOSHI KONNO
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Keywords: hypoxic vasoconstriction, isoproterenol, lung denervation, propranolol, reimplanted lung
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1982 Volume 136 Issue 2 Pages 163-168

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Abstract
ISAWA, T., TESHIMA, T., HIRANO, T., EBINA, A., SHIRAISHI, K., FUKUDA, Y., and KONNO, K. Effect of Isoproterenol on Regional Pulmonary Perfusion in the Reimplanted Lung of the Dog. Tohoku J. exp. Med., 1982, 136 (2), 163-168-In the reimplanted lung lobe of the dog, regional pulmonary hypoxic vasoconstriction did not occur when isoproterenol was administered and the pharmacological action of isoproterenol in the reimplanted lung lobe was not antagonized by propranolol, whereas propranolol did block its action in the heart depressing the cardiac rate.
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