The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
A Method for Determination of Human Urinary Inactive Kallikrein (Prekallikrein)
KAZUAKI SHIMAMOTOJULIE CHAOHARRY S. MARGOLIUS
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1982 Volume 137 Issue 3 Pages 269-274

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Abstract

SHIMAMOTO, K., CHAO, J. and MARGOLIUS, H.S. A Method for Determination of Human Urinary Inactive Kallikrein (Prekallikrein). Tohoku J. exp. Med., 1982, 137 (3), 269-274-Inactive kallikrein (prekallikrein) in human urine was discovered recently. A more accurate method to measure this zymogen and total kallikrein is described. With trypsin pretreatment, it was found that 35.3±2.7% of total urinary kallikrein activity was prekallikrein. The results are supported by a new direct radioimmunoassay which measures predominantly active kallikrein.

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