The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Decreased Membrane Fragility of Mouse Erythrocytes by Small Dose of Methylmercury and Its Restoration by Coadministered Selenite
REIKO YAMAMOTOTSUGUYOSHI SUZUKI
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1982 年 137 巻 3 号 p. 297-303

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YAMAMOTO, R. and SUZUKI, T. Decreased Membrane Fragility of Mouse Erythrocytes by Small Dose of Methylmercury and Its Restoration by Coadministered Selenite. Tohoku J. exp. Med., 1982, 137 (3), 297-303-Female IVCS mice were fed methylmercury at a low dose level (10nmoles/g feed) with coadministration of selenite (0, 8, 20 or 50nmoles/ml of drinking water) for one week or two weeks. Mice fed methylmercury alone showed the decreased fragility of erythrocytes membrane when compared with the non-treated control. Coadministration of selenite produced such a change to smaller extents than methylmercury treatment alone. Mercury levels in the blood varied according to the dose level of selenite (the highest level was found in methylmercury alone group).
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© Tohoku University Medical Press
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