Interaction of Sisomycin with Pancuronium
1983 Volume 139 Issue 2 Pages 217-218
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1983 Volume 139 Issue 2 Pages 217-218
HASHIMOTO, Y. Interaction of Sisomycin with Pancuronium. Tohoku J. exp. Med., 1983, 139 (2), 217-218-The effect of sisomycin sulfate (75mg) on the neuromuscular junction was studied in anesthetized patients. Sisomycin sulfate alone did not depress twitch tension. When twitch tension after pancuronium had recovered to 50% of the control level, i.v. administration of sisomycin sulfate caused a decrease in twitch tension. The combined sisomycin-pancuronium-induced blockade was antagonized by calcium chloride (400mg) or edrophonium (10mg).
