The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Enflurane Induces Contracture of in Vitro Muscle from a Patient with Malignant Hyperthermia
NAOFUMI IWATSUKIYOSHIHISA KOGAKEISUKE AMAHA
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1983 Volume 140 Issue 2 Pages 221-222

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Abstract
IWATSUKI, N., KOGA, Y. and AMAHA, K. Enflurane Induces Contracture of in Vitro Muscle from a Patient with Malignant Hyperthermia. Tohoku J. exp. Med., 1983, 140 (2), 221-222 - The possibility of enflurane being an inducer of malignant hyperthermia (MH) was examined by using the contracture test in in vitro muscle from a patient with MH. An administration of 2% enflurane elicited contracture in MH muscle and an elimination of enflurane relaxed this contracture. This result, therefore, strongly suggested that enflurane is the one of the trigger-agents for MH.
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© Tohoku University Medical Press
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