A 10 Year Follow-Up of Diabetes in a Rural Area of Japan Using the 50g Oral Glucose Tolerance Test

Abstract

We performed a 10 year follow-up study on diabetics using the 50g oral glucose tolerance test in a rural area of Japan. In untreated borderline diabetics, high or normal insulin responders became normal for glucose tolerance 10 years later. However, low insulin responders became overt diabetics or remained borderline diabetics. Therefore, insulinogenic index was considered to be one of the most valuable indexes in the prospective investigation of untreated borderline diabetics.