Abstract
MORITA, T., SUZUKI, T., KONDO, S., SAEKI, H, and TSUCHIDA, S. Response of the Renal Pacemaker to β1-Adrenoceptor Agonist: Difference from the Cardiac Pacemaker. Tohoku J. exp. Med., 1984, 143 (4), 409-412 - Electromyographic responses of the canine-pyeloureter to dobutamine, a β1-adrenoceptor agonist were investigated in vitro. Debutamine produced a marked enhancement of potential in the pelvicalyceal (PC-) border, but failed to evoke noticeable responses in the renal pelvis and ureter. Dobutamine, however, made the pacemaker rhythm a little slow. This finding shows that the renal pacemaker is somewhat different form the cardiac pacemaker, pace of which is quickened by dobutamine.
