The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Determination of Urine Neuron-Specific Enolase Levels in Neuroblastoma Patients
YOH-ICHI GOTOHKUMIKO HASHIMOTOSHIGEO INOUEJUN SUZUKIKEIYA TADA
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1985 年 147 巻 4 号 p. 429-430

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GOTOH, Y-I., HASHIMOTO, K., INOUE, S., SUZUKI, J. and TADA, K. Determination of Urine Neuron-Specific Enolase Levels in Neuroblastoma Patients. Tohoku J. exp. Med., 1985, 147 (4), 429-430-Urine levels of neuron-specific enolase were determined in 3 neuroblastoma patients (1 in an advanced state and 2 in remission), 25 control children, 37 control adults and 4 children with hematuria by means of the double-antibody inhibition radioimmunoassay specific to the γ subunit of enolase isozymes. The levels of neuron-specific enolase mean±S.D. ng/creatinine mg in an advanced neuroblastoma patient were elevated (1.25±0.29 before or after treatment and range 1.61-74.2 during treatment) when compared with those of control subjects (0.51±0.26 in children and 0.36±0.17 in adults). The levels in 2 neuroblastoma patients in remission were within normal range. Urine samples with hematuria were not used for the assay.
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