The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on the Detoxicating Hormone of the Liver (Yakriton)
23rd Report. Prophylactic Effect of Yakriton against Acute Phosphorus Poisoning
KYUMATSU ASAKURA
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1930 Volume 15 Issue 5-6 Pages 476-480

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Abstract
Yakriton, the detoxicating hormone of the liver, can save rabbits not only from subacute phosphorus poisoning but also from acute phosphorus poisoning. For the latter purpose 1/4 R. A. U. of yakriton exerts a very much better effect than other numbers of units larger or smaller, because these can make animals live only longer than controls at best. It is very peculiar that 1/2 R. A. U. exerts the best prophylactic effect in subacute phosphorus poisoning and that 1/4 R. A. U., half of 1/2 R. A. U., exerts the best effect in acute phosphorus poisoning, poisoning with twice as large an amount of phosphorus as in the case of subacute phosphorus intoxication.
Of course the prevention of acute phosphorus poisoning is more difficult than that of subacute intoxication.
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