Abstract
SHIMIZU, K., OGAWA, K.B., KATO, T., LEE, J-D., HARA, A. and NAKAMURA, T. Complete Prevention of Acetylcholine Induced Coronary Artery Spasm with Nifedipine. Tohoku J. exp. Med., 1988, 154 (1), 93-94 - A 63-year-old woman has been known to have angina pectoris due to coronary artery (CA) spasm. An intra-left CA infusion of acetylcholine (ACh) provoked spasms of the left CA and an anginal attack. After daily oral administration of nifedipine (NIF) for 2 weeks, intra-CA re-infusion study of ACh did not provoke any CA spasms. This is the first report to demonstrate the complete prevention of ACh-induced CA spasm with nifedipine
