Efficacy of Absolute Ethanol Injection for Upper Gastrointestinal Massive Bleedings with Hemorrhagic Shock

SHIGERU ASAKI; TOSHIAKI NISHIMURA; AKIRA SATO; RIN YAMAGATA; SHUNJI OKUBO; TOKIAKI TOYOHARA; YASUTOSHI SAITO; SHOICHIRO ITO; SHINGO MIYAZAKI

doi:10.1620/tjem.156.7

SHIGERU ASAKI, TOSHIAKI NISHIMURA, AKIRA SATO, RIN YAMAGATA, SHUNJI OKUBO, TOKIAKI TOYOHARA, YASUTOSHI SAITO, SHOICHIRO ITO, SHINGO MIYAZAKI

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Keywords: UGI bleeding, endoscopic hemostasis, absolute ethanol injection method, cases with hemorrhagic shock

JOURNAL FREE ACCESS

1988 Volume 156 Issue 1 Pages 7-11

DOI https://doi.org/10.1620/tjem.156.7

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Published: 1988 Received: April 25, 1988 Available on J-STAGE: August 31, 2006 Accepted: July 30, 1988 Advance online publication: - Revised: -
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Date of correction: August 31, 2006 Reason for correction: - Correction: ABSTRACT Details: Wrong : ASAKI, S., NISHIMURA, T., SATO, A., YAMAGATA, R., OKUBO, S., TOYOHARA, T., SAITO, Y., ITO, S. and MIYAZAKI, S. Efficacy of Absolute Ethanol Injection for Upper Gastrointestinal Massive Bleedings with Hemorrhagic Shock. Tohoku J. exp. Med., 1988, 156 (1), 7-11-We applied the absolute ethanol injection method in 182 cases of massive bleeding with hemorrhagic shock before the performance of emergency endoscopy in 627 cases of upper gastrointestinal bleeding at our department and five related institutions since June 1979. Following results were obtained: Temporary hemostasis could not be obtained in only 2 (1.1%) out of 182 cases; in the remaining 180 cases bleeding was ceased. Rebleeding was seen in 15 cases (8.2%) and new bleeding in 17 cases (9.3%). In 21(66%) of these cases hemostasis was obtained again by the absolute ethanol injection method. Eight patients (4.4%) underwent emergency operation and 4 patients (2.2%) died from bleeding. The complete hemostasis was obtained in 170 cases (93.4%).
Right : We applied the absolute ethanol injection method in 182 cases of massive bleeding with hemorrhagic shock before the performance of emergency endoscopy in 627 cases of upper gastrointestinal bleeding at our department and five related institutions since June 1979. Following results were obtained: Temporary hemostasis could not be obtained in only 2 (1.1%) out of 182 cases; in the remaining 180 cases bleeding was ceased. Rebleeding was seen in 15 cases (8.2%) and new bleeding in 17 cases (9.3%). In 21 (66%) of these cases hemostasis was obtained again by the absolute ethanol injection method. Eight patients (4.4%) underwent emergency operation and 4 patients (2.2%) died from bleeding. The complete hemostasis was obtained in 170 cases (93.4%).

Date of correction: August 31, 2006 Reason for correction: - Correction: CITATION Details: Wrong : 1) Asaki, S. (1981) Tissue solidification in coping with digestive tract bleeding: Hemostatic effect of local injection of 99.5% ethanol. Tohoku J. exp. Med., 134, 223-227.
2) Asaki, S. (1984) Endoscopic hemostasis by local absolute ethanol injection for upper G-I tract bleeding-a multi-center study. In: Endoscopic Surgery, edited by H. Okabe, T. Honda & S. Oshiba, Elsevier Publishing Co., New York, pp. 105-116.
3) Chen, P., Wu, C. & Liaw, Y. (1986) Hemostatic effect of endoscopic local injection with hypertonic saline-epinephrine solution and pure ethanol for digestive tract bleeding. Gastroent. Endoscopy, 32, 319-323.
4) Kiefhaber, P., Kiefhaber, K., Huber, F. & Nath, G. (1986) Endoscopic Neodymium: YAG laser coagulation in gastrointestinal hemorrhage. Endoscopy, 18, 46-51, (Suppl. 2.
5) Oshita, Y., Okazaki, Y., Ariyama, S., Asagami, F., Tada, M., Harada, H., Saito, M., Watanabe, S., Uchida, Y., Hirata, M., Kawahara, K., Odawara, M., Sasaki, N., Iida, Y., Kawamura, S., Takemoto, T., Tanabe, M., Sasayama, T., Nagai, K., Hayashi, K. & Tamura, Y. (1982) Comparative study on endoscopic Nd-YAG and Argon laser photocoagulation in the treatment of upper gastrointestinal hemorrhage. Gastroent. Endoscopy, 24, 557-562. (Japanese)
6) Sugawa, C., Fujita, Y., Ikeda, T. & Walt, A. J. (1986) Endoscopic hemostasis of bleeding of the upper gastrointestinal tract by local injection of ninety-eight per cent dehydrated ethanol. Surg. Gynec. Obstet., 162, 159-163.

Right : 1) Asaki, S. (1981) Tissue solidification in coping with digestive tract bleeding: Hemostatic effect of local injection of 99.5% ethanol. Tohoku J. exp. Med., 134, 223-227.
2) Asaki, S. (1984) Endoscopic hemostasis by local absolute ethanol injection for upper G-I tract bleeding - a multi-center study. In: Endoscopic Surgery, edited by H. Okabe, T. Honda & S. Oshiba, Elsevier Publishing Co., New York, pp. 105-116.
3) Chen, P., Wu, C. & Liaw, Y. (1986) Hemostatic effect of endoscopic local injection with hypertonic saline-epinephrine solution and pure ethanol for digestive tract bleeding. Gastroent. Endoscopy, 32, 319-323.
4) Kiefhaber, P., Kiefhaber, K., Huber, F. & Nath, G. (1986) Endoscopic Neodymium: YAG laser coagulation in gastrointestinal hemorrhage. Endoscopy, 18, 46-51, (Suppl. 2.
5) Oshita, Y., Okazaki, Y., Ariyama, S., Asagami, F., Tada, M., Harada, H., Saito, M., Watanabe, S., Uchida, Y., Hirata, M., Kawahara, K., Odawara, M., Sasaki, N., Iida, Y., Kawamura, S., Takemoto, T., Tanabe, M., Sasayama, T., Nagai, K., Hayashi, K. & Tamura, Y. (1982) Comparative study on endoscopic Nd-YAG and Argon laser photocoagulation in the treatment of upper gastrointestinal hemorrhage. Gastroent. Endoscopy, 24, 557-562. (Japanese)
6) Sugawa, C., Fujita, Y., Ikeda, T. & Walt, A. J. (1986) Endoscopic hemostasis of bleeding of the upper gastrointestinal tract by local injection of ninety-eight per cent dehydrated ethanol. Surg. Gynec. Obstet., 162, 159-163.

Date of correction: August 31, 2006 Reason for correction: - Correction: PDF FILE Details: -

Abstract

We applied the absolute ethanol injection method in 182 cases of massive bleeding with hemorrhagic shock before the performance of emergency endoscopy in 627 cases of upper gastrointestinal bleeding at our department and five related institutions since June 1979. Following results were obtained: Temporary hemostasis could not be obtained in only 2 (1.1%) out of 182 cases; in the remaining 180 cases bleeding was ceased. Rebleeding was seen in 15 cases (8.2%) and new bleeding in 17 cases (9.3%). In 21 (66%) of these cases hemostasis was obtained again by the absolute ethanol injection method. Eight patients (4.4%) underwent emergency operation and 4 patients (2.2%) died from bleeding. The complete hemostasis was obtained in 170 cases (93.4%).

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