Effect of Immunoglobulin Preparation on Course of AIDS-Related Complex (ARC)

TATSUHARU OHNO; TADASHI KANOH; HARUTO UCHINO; SHINJI HARADA

doi:10.1620/tjem.156.415

TATSUHARU OHNO, TADASHI KANOH, HARUTO UCHINO, SHINJI HARADA

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Keywords: acquired immunodeficiency syndrome (AIDS), AIDS-related complex (ARC), immunoglobulin preparation

JOURNAL FREE ACCESS

1988 Volume 156 Issue 4 Pages 415-416

DOI https://doi.org/10.1620/tjem.156.415

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Published: 1988 Received: August 15, 1988 Available on J-STAGE: August 31, 2006 Accepted: October 19, 1988 Advance online publication: - Revised: -
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Date of correction: August 31, 2006 Reason for correction: - Correction: ABSTRACT Details: Wrong : OHNO, T., KANOH, T., UCHINO, H. and HARADA, S. Effect of Immunoglobulin Preparation on Course of AIDS-Related Complex (ARC). Tohoku J. exp. Med., 1988, 156 (4), 415-416-Relatively low dose treatment (150mg kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inversion of CD4/CD8 ratio, this type of IVI treatment seems to be effective for obstructing or at least delaying the progression from ARC to AIDS.
Right : Relatively low dose treatment (150 mg/kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inversion of CD4/CD8 ratio, this type of IVI treatment seems to be effective for obstructing or at least delaying the progression from ARC to AIDS.

Date of correction: August 31, 2006 Reason for correction: - Correction: CITATION Details: Wrong : 1) Calvelli, T.A. & Rubinstein, A. (1986) Intravenous gammaglobulin in infant acquired immunodeficiency syndrome. Pediatr. infect. Dis. J., 5, 207-210.
2) Gupta, A., Novic, B.E. & Rubinstein, A. (1986) Restoration of suppressor T-cell functions in children with AIDS following intravenous gammaglobulin treatment. Amer. J. Dis. Child., 140, 143-146.
3) Ochs, H.D. (1987) Intravenous immunoglobulin in the treatment and prevention of acute infections in pediatric acquired immunodeficiency syndrome patients. Pediatr. infect. Dis. J., 6, 509-511.
4) Ohno, T., Kanoh, T., Uchino, H. & Miyachi, Y. (1987) Clinical features and immunological characteristics of a male homosexual with AIDS-related complex in whom HIV was strongly suspected to be transmitted via his partner. Acta haematol. jap., 49, 1007-1013.
5) Sedlecek, H.H., Gronski, P. & Hofstaetter, T. (1983) The biological properties of immunoglobulin G and its split products [F(ab')₂ and Fab]. Klin. Wschr., 61, 723-736.

Right : 1) Calvelli, T. A. & Rubinstein, A. (1986) Intravenous gammaglobulin in infant acquired immunodeficiency syndrome. Pediatr. infect. Dis. J., 5, 207-210.
2) Gupta, A., Novic, B. E. & Rubinstein, A. (1986) Restoration of suppressor T-cell functions in children with AIDS following intravenous gammaglobulin treatment. Amer. J. Dis. Child., 140, 143-146.
3) Ochs, H. D. (1987) Intravenous immunoglobulin in the treatment and prevention of acute infections in pediatric acquired immunodeficiency syndrome patients. Pediatr. infect. Dis. J., 6, 509-511.
4) Ohno, T., Kanoh, T., Uchino, H. & Miyachi, Y. (1987) Clinical features and immunological characteristics of a male homosexual with AIDS-related complex in whom HIV was strongly suspected to be transmitted via his partner. Acta haematol. jap., 49, 1007-1013.
5) Sedlecek, H. H., Gronski, P. & Hofstaetter, T. (1983) The biological properties of immunoglobulin G and its split products [F(ab')₂ and Fab]. Klin. Wschr., 61, 723-736.

Date of correction: August 31, 2006 Reason for correction: - Correction: PDF FILE Details: -

Abstract

Relatively low dose treatment (150 mg/kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inversion of CD4/CD8 ratio, this type of IVI treatment seems to be effective for obstructing or at least delaying the progression from ARC to AIDS.

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