1990 年 160 巻 1 号 p. 1-9
KURATA, T., KONDO, T., HAYASHI, Y., OHTA, Y. and YAMABAYASHI, H. Continuous Positive Airway Pressure Breathing in Supine and Upright Postures. Tohoku J. Exp. Med., 1990, 160 (1), 1-9-Continuous positive airway pressure (CPAP) breathing of 10cmH2O was applied to 10 healthy conscious subjects both in supine and 70 degree head-up postures. CPAP increased the end-expiratory lung volume from 2.44±0.66 (S.D.) to 3.07±0.68 liters in supine subjects, and from 3.01±0.57 to 3.64±0.57 liters in head-up subjects. During CPAP, rib cage motion became predominant when compared to abdominal motion in upright posture. Among the respiratory parameters, inspiratory duration was significantly shortened during CPAP in either posture, but was changed less significantly by individual posture change alone. Mean inspiratory flow decreased during CPAP only in upright posture. Abdominal muscles were recruited for expiration during CPAP in either posture, and the EMG recorded from the lower intercostal space developed inspiratory activity during CPAP in head-up posture. All of 10 subjects felt most dyspneic during CPAP with the head-up. We conclude that the mechanism of increase in lung volume during CPAP is mediated by different pathway from that of posture change, and that CPAP in upright posture can alter the respiratory pattern of the subject.
