The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Permanent Brain Damage Possibly Caused by Theophylline in Two Elderly Patients with Airway Obstruction
KIYOHISA SEKIZAWA, TAKASHI AIKAWA, MASARU YANAI, SIGERU ITABASHI, TAKEYASU FUKUSHIMA, HIDETADA SASAKI
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Keywords: theophylline, bronchial asthma, chronic pulmonary obstructive disease, convulsion, brain damage
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1990 Volume 162 Issue 4 Pages 303-307

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Abstract
SEKIZAWA, K., AIKAWA, T., YANAI, M., ITABASHI, S., FUKUSHIMA, T. and SASAKI, H. Permanent Brain Damage Possibly Caused by Theophylline in Two Elderly Patients with Airway Obstruction. Tohoku J. Exp. Med., 1990, 162 (4), 303-307 - Two aged patients with bronchial asthma and chronic obstructive pulmonary disease who suffered convulsions that resulted in permanent brain damage during treatment with the recommended therapeutic dose of theophylline are presented here. A dose or concentration of theophylline lower than the recommended one should be considered in the treatment of some aged patients with pulmonary obstructive disease.
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